393 research outputs found

    The effects of integrating mobile devices with teaching and learning on students' learning performance: A meta-analysis and research synthesis

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    AbstractMobile devices such as laptops, personal digital assistants, and mobile phones have become a learning tool with great potential in both classrooms and outdoor learning. Although there have been qualitative analyses of the use of mobile devices in education, systematic quantitative analyses of the effects of mobile-integrated education are lacking. This study performed a meta-analysis and research synthesis of the effects of integrated mobile devices in teaching and learning, in which 110 experimental and quasiexperimental journal articles published during the period 1993ā€“2013 were coded and analyzed. Overall, there was a moderate mean effect size of 0.523 for the application of mobile devices to education. The effect sizes of moderator variables were analyzed and the advantages and disadvantages of mobile learning in different levels of moderator variables were synthesized based on content analyses of individual studies. The results of this study and their implications for both research and practice are discussed

    Detach and Adapt: Learning Cross-Domain Disentangled Deep Representation

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    While representation learning aims to derive interpretable features for describing visual data, representation disentanglement further results in such features so that particular image attributes can be identified and manipulated. However, one cannot easily address this task without observing ground truth annotation for the training data. To address this problem, we propose a novel deep learning model of Cross-Domain Representation Disentangler (CDRD). By observing fully annotated source-domain data and unlabeled target-domain data of interest, our model bridges the information across data domains and transfers the attribute information accordingly. Thus, cross-domain joint feature disentanglement and adaptation can be jointly performed. In the experiments, we provide qualitative results to verify our disentanglement capability. Moreover, we further confirm that our model can be applied for solving classification tasks of unsupervised domain adaptation, and performs favorably against state-of-the-art image disentanglement and translation methods.Comment: CVPR 2018 Spotligh

    The modality effect in a mobile learning environment: Learning from spoken text and real objects

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    The finding that under split-attention conditions students learn more from a picture and spoken text than from a picture and written text (ie, the modality effect) has consistently been found in many types of computer-assisted multimedia learning environments. Using 58 fifth-grade and sixth-grade elementary school children as participants, we investigated whether the modality effect can also be found in a mobile learning environment (MLE) on plants' leaf morphology, in which students had to learn by integrating information from text and real plants in the physical environment. A single factor experimental design was used to examine the hypothesis that students in a mixed-mode condition with real plants and spoken text (STP condition) would pay more attention to the real plants, and achieve higher performance on retention, comprehension, and transfer tests than the single-mode condition with real plants and written text (WTP condition). Whereas we found that participants in the STP condition paid more attention to observing the plants, and achieved a higher score on the transfer test than participants in the WTP condition, no differences were found between the conditions for retention and comprehension test performance

    A Comparison of Food-grade Folium mori Extract and 1-Deoxynojirimycin for Glycemic Control and Renal Function in Streptozotocin-induced Diabetic Rats

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    ABSTRACTFolium mori (ꔑ葉 Sāng YĆØ, leaf of Morus alba L.; FM) is known to possess hypoglycemic effects, and 1-deoxynojirimycin (1-DNJ) has been proposed as an important functional compound in FM. However, the hypoglycemic activity of purified 1-DNJ has been rarely studied. It is also not known how FM and 1-DNJ affect the development of DM nephropathy. This study compared the antidiabetic effect of a commercial FM product with that of purified 1-DNJ in streptozotocin-induced diabetic rats. Seven days after induction, the diabetic rats were gavaged with FM (1, 3, 10, and 30mg/kg/day), 1-DNJ (30mg/kg/day), or vehicle (distilled deionized water; 2ml/kg/day) for 7days. All doses of FM ameliorated fasting and post-prandial blood glucose concomitantly with an increase in peripheral and pancreatic levels of insulin and improved homeostasis model assessment (HOMA-IR) in diabetic rats in a dose-dependent manner. Increased thiobarbituric acid reactive substances (TBARS) and nitrate/nitrite levels in the kidney, liver, and muscle of diabetic rats were reversed by all doses of FM. The renal function of the diabetic rats was normalized by all doses of FM, while blood pressure changes were reversed by FM at doses of 3mg/kg and above. Moreover, most of the above-mentioned parameters were improved by FM at doses of 3mg/kg and above to a similar extent as that of 1-DNJ. The results showed superior antidiabetic potential of the commercial FM product for glycemic control and protection against the development of diabetic nephropathy

    Functional roles of arginine residues in mung bean vacuolar H+-pyrophosphatase

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    AbstractPlant vacuolar H+-translocating inorganic pyrophosphatase (V-PPase EC 3.6.1.1) utilizes inorganic pyrophosphate (PPi) as an energy source to generate a H+ gradient potential for the secondary transport of ions and metabolites across the vacuole membrane. In this study, functional roles of arginine residues in mung bean V-PPase were determined by site-directed mutagenesis. Alignment of amino-acid sequence of K+-dependent V-PPases from several organisms showed that 11 of all 15 arginine residues were highly conserved. Arginine residues were individually substituted by alanine residues to produce Rā†’A-substituted V-PPases, which were then heterologously expressed in yeast. The characteristics of mutant variants were subsequently scrutinized. As a result, most Rā†’A-substituted V-PPases exhibited similar enzymatic activities to the wild-type with exception that R242A, R523A, and R609A mutants markedly lost their abilities of PPi hydrolysis and associated H+-translocation. Moreover, mutation on these three arginines altered the optimal pH and significantly reduced K+-stimulation for enzymatic activities, implying a conformational change or a modification in enzymatic reaction upon substitution. In particular, R242A performed striking resistance to specific arginine-modifiers, 2,3-butanedione and phenylglyoxal, revealing that Arg242 is most likely the primary target residue for these two reagents. The mutation at Arg242 also removed Fāˆ’ inhibition that is presumably derived from the interfering in the formation of substrate complex Mg2+ā€“PPi. Our results suggest accordingly that active pocket of V-PPase probably contains the essential Arg242 which is embedded in a more hydrophobic environment

    Sibling recurrence risk ratio analysis of the metabolic syndrome and its components over time

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    BACKGROUND: The purpose of this study was to estimate both cross-sectional sibling recurrence risk ratio (Ī»(s)) and lifetime Ī»(s )for the metabolic syndrome and its individual components over time among sibships in the prospectively followed-up cohorts provided by the Genetic Analysis Workshop 13. Five measures included in the operational criteria of the metabolic syndrome by the Adult Treatment Panel III were examined. A method for estimating sibling recurrence risk with correction for complete ascertainment was used to estimate the numerator, and the prevalence in the whole cohort was used as the denominator of Ī»(s). RESULTS: Considerable variability in the Ī»(s )was found in terms of different time-points for the cross-sectional definition, the times of fulfilling the criterion for lifetime definition, and different components. Obesity and hyperglycemia had the highest cross-sectional Ī»(s )of the five components. Both components also had the largest slopes in the linear trend of the lifetime Ī»(s). However, the magnitudes of the lifetime Ī»(s )were similar to that of the mean cross-sectional Ī»(s), which were <2. The results of nonparametric linkage analysis showed only suggestive evidence of linkage between one marker and lifetime diagnosis of low high-density lipoprotein cholesterol and metabolic syndrome, respectively. CONCLUSION: The Ī»(s )of the metabolic syndrome and its components varies substantially across time, and the Ī»(s )of lifetime diagnosis was not necessarily larger than that of a cross-sectional diagnosis. The magnitude of Ī»(s )does not predict well the maximum LOD score of linkage analysis

    Percutaneous transhepatic techniques for retrieving fractured and intrahepatically dislodged percutaneous transhepatic biliary drainage catheters

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    Dislodged intrabiliary drainage devices, including catheters, endoprostheses, and stents, may further impair drainage and cause various local reactions, vascular and gastrointestinal tract complications. Endoscopic approaches for management of plastic biliary endoprostheses have been extensively discussed. However, in rare cases of fracture of percutaneous transhepatic biliary drainage (PTBD) catheters, only a percutaneous transhepatic technique for retrieving should be applied to avoid further damage by its rigid fragment. We present the adjusted techniques using either a goose neck snare, over-the-wire balloon catheter, or biopsy forceps with image demonstration and reviews. We encountered two patients with PTBD tube fracture and intrahepatic dislodgment. In both patients, percutaneous approaches were used for successfully retrieving and removing the fractured catheter through transhepatic tract: one with the use of a biopsy forceps, another with an inflatable balloon catheter
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